Evaluation of Serum and Ocular Coherence Tomography Biomarkers in Patients With Diabetic Macular Edema Treated With Anti-VEGF or Dexamethasone Implant
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other, Drug, Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study aims to investigate the association between serum biomarkers and clinical response to anti-VEGF or dexamethasone implant by assessing OCT-biomarkers in patients with diabetic macular edema, DME, and to compare these with a group of naive patients (those not previously treated for DME).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Type I or type II DM.
• DME involving the center of the fovea with CFT more than 280 microns and the presence of intraretinal cysts.
Locations
Other Locations
Sweden
Ögonmottagning Mölndal/SU
NOT_YET_RECRUITING
Mölndal
Sahlgrenska University Hospital, Department of Ophthalmology
RECRUITING
Mölndal
Contact Information
Primary
Imadeddin Abu Ishkheidem, M.D.
imadeddin.abu.ishkheidem@vgregion.se
+46738744867
Backup
Sofia Töyrä Silfverswärd, PhD
sofia.toyra.silfversward@vgregion.se
0761283085
Time Frame
Start Date: 2025-08-01
Estimated Completion Date: 2028-12-31
Participants
Target number of participants: 150
Treatments
Experimental: Anti-VEGF treated patients
Patients with ongoing anti-VEGF treatment
Experimental: Dexamethasone treated patients
Patients with ongoing Dexamethasone implant treatment
Experimental: Patients not previously treated for DME
Treatment-naive patients (neither anti-VEGF treatment nor Dexamethasone implant treatment)
Related Therapeutic Areas
Sponsors
Leads: Vastra Gotaland Region